The other is that people with good intentions will inadvertently cause harm.'Д«ut for treating classic genetic diseases like sickle cell, I think CRISPR will be transformative,вЂќ he adds, вЂњand thatвЂ™s a great thing.вЂќ Living day to day вЂњOne is the intentional misuse of CRISPR. вЂњWhen it comes to experiments on animals, plants and microbes, two things worry me,вЂќ says Stanford bioethicist Hank Greely, JD, a professor of law. Laboratories have already used CRISPR to engineer bigger tomatoes, longer-lasting mushrooms and leaner pigs for CRISPR bacon - items that may one day appear on your grocery shelf. Others are concerned about ongoing experiments to alter the DNA of disease-spreading insects and to genetically enhance crops and livestock, in part because of unintended impacts on the environment. Some fear that CRISPR will be used to create designer babies with desirable physical traits and talents. Barely a week goes by without news of another CRISPR вЂњbreakthrough.вЂќ But the rapid pace of discovery has raised questions about the regulation and oversight of this gene-altering tool. вЂњWith CRISPR, we can do genetic experiments that would have been unimaginable just a few years ago, not just on inherited disorders but also on genes that contribute to acquired diseases, including AIDS, cancer and heart diseases.'Д¬RISPR was introduced to the world in 2012, and the technology has since generated a tsunami of research. вЂњItвЂ™s no exaggeration to say that CRISPR has been revolutionary,вЂќ says Mark Mercola, PhD, a professor of cardiovascular medicine and a member of the Stanford Cardiovascular Institute. Other gene-editing tools have emerged in recent years, but none seems to match the precision, low cost and usability of CRISPR, which is rapidly transforming genetic research and has entered testing as a medical treatment. But what if his genetic disease - and thousands of others - could be cured by simply fixing the mutation? Researchers are betting they can with CRISPR, a powerful technology that allows scientists to quickly target, delete and repair any mutated sequence of DNA in any gene. DavidвЂ™s monthly infusions offer only temporary relief from the debilitating and potentially deadly complications of his disease.

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